The selection of surfactants should be based on the characteristics of the original drug

2021-07-23 11:00:30

Pesticide is usually prepared into liquid by its pesticide preparation, and then sprayed on crops. The pesticide preparation is made by adding various surfactants on the basis of the original pesticide. In practical application, not only a single adjuvant is used. In order to improve the efficacy, a variety of adjuvants can be used at the same time, but the interaction between all kinds of adjuvants must be paid attention to, so as to prevent the unnecessary photodegradation of pesticides and reduce the efficacy.

In the same dosage form, different kinds of additives will also significantly affect the performance of the agent. For example, the selection of inappropriate wetting agent and dispersant will not only reduce the suspension rate of wettable powder and suspending agent, but also affect the absorption of the agent on the leaf surface, which is particularly important in pesticide preparations for stem and leaf treatment. Therefore, the selection of surfactants should not only select the varieties according to the properties and characteristics of the original drug, but also consider the impact of the surfactant itself on the original drug and target organisms.

It is an efficient rapid disintegrating agent with good water absorption and expansibility. After full expansion, the volume can be increased by 200 ~ 300 times, and it does not form a viscous solution in water to hinder the continuous disintegration of tablets. For example, as a tablet filler, microcrystalline cellulose has the functions of dilution, adhesion and disintegration. It is a kind of multi-functional auxiliary material, which is not only helpful for tablet pressing, but also has a certain disintegration. Because of its water absorption, even if the wetting agent is slightly excessive, it will not affect the mixing and sieving of the wet material, and it can still produce more uniform particles without caking, In wet granulation, the fluidity and compressibility of particles can be significantly improved. It is proved that the same effect can be obtained by using powdered cellulose vttacel M80 and vttacel.p290.

Effervescent tablet (or granule) is a very convenient new pesticide dosage form. It is proposed for the specific environment with water in rice field. It is composed of active ingredients, surfactants and carriers. When in use, the tablet (or granule) is directly put into the water field. The carbonate and organic acid in the agent react rapidly with water to produce carbon dioxide gas, which makes it effervescent and disintegrate rapidly to form a uniform viscous suspension. Through the action of its own diffuser, it diffuses evenly around, so that the effective components contact the target and exert their efficacy; It has the advantages of quick absorption, high bioavailability, no need of spraying or mixing with soil, accurate measurement, easy measurement, no dust flying, little environmental pollution, easy to use and welcomed by users.